Ginger Root

Source

A Ginger Root source containg 5% gingerols is the highest quality and very potent form of ginger used for Mymmunity

Botanical Details

Family: Zingiberaceae

Genus: Zingiber

Species: Z. officinale

Immune support

Preliminary clinical research in patients with rheumatoid arthritis (RA) shows that ginger increases FoxP3 gene expression. This allows for proper development of regulatory T cells, which help suppress the autoimmune response of effector T cells. Ginger also appears to decrease the expression of the ROR gamma t and T-bet genes, both of which are believed to be involved in the autoimmune process.

Other uses

Nausea and vomiting caused by drugs used to treat HIV/AIDS (antiretroviral-induced nausea and vomiting). Research suggests that taking ginger daily, 30 minutes before each dose of antiretroviral treatment for 14 days, reduces the risk of nausea and vomiting in patients receiving HIV treatment.

Menstrual cramps (dysmenorrhea). Research shows that taking ginger powder 500-2000 mg during the first 3-4 days of a menstrual cycle modestly decreases pain in women and teens with painful menstrual periods. Ginger was given for approximately 3 days starting at the beginning of the menstrual period or at the beginning of pain. Some research shows that taking ginger seems to work about as well as some pain medications, like ibuprofen, mefenamic acid, or Novafen. Adding ginger to medicines such as mefenamic acid also seems to be helpful.

Osteoarthritis. Most research shows that taking ginger by mouth can slightly reduce pain in some people with osteoarthritis. There is some evidence that taking ginger by mouth works as well as certain drugs such as ibuprofen and diclofenac for pain in hip and knee osteoarthritis. But conflicting results exist. Some early research also shows that ginger gel applied to the knee or ginger oil massaged into the knee can also relieve osteoarthritis pain.

Morning sickness. Taking ginger by mouth seems to reduce nausea and vomiting in some pregnant women. But it might work slower or not as well as some drugs used for nausea. Also, taking any herb or medication during pregnancy is a big decision. Before taking ginger, be sure to discuss the possible risks with your healthcare provider.


How it works

Ginger contains chemicals that may reduce nausea and inflammation. Researchers believe the chemicals work primarily in the stomach and intestines, but they may also work in the brain and nervous system to control nausea.

Safety

When taken by mouth: Ginger is LIKELY SAFE when taken appropriately. Ginger can cause mild side effects including heartburn, diarrhea, and general stomach discomfort. Some women have reported extra menstrual bleeding while taking ginger.

When applied to the skin: Ginger is POSSIBLY SAFE when applied to the skin appropriately, short-term. It might cause irritation on the skin for some people.

Special Precautions & Warnings:

Pregnancy: Ginger is POSSIBLY SAFE when taken by mouth for medicinal uses during pregnancy. But using ginger during pregnancy is controversial. There is some concern that ginger might affect fetal sex hormones or increase the risk of having a baby that is stillborn. There is also a report of miscarriage during week 12 of pregnancy in a woman who used ginger for morning sickness. However, most studies in pregnant women suggest that ginger can be used safely for morning sickness without harm to the baby. The risk for major malformations in infants of women taking ginger does not appear to be higher than the usual rate of 1% to 3%. Also there doesn't appear to be an increased risk of early labor or low birth weight. There is some concern that ginger might increase the risk of bleeding, so some experts advise against using it close to your delivery date. As with any medication given during pregnancy, it's important to weigh the benefit against the risk. Before using ginger during pregnancy, talk it over with your healthcare provider.

Children: Ginger is POSSIBLY SAFE when taken by mouth for up to 4 days by teenage girls around the start of their period.

Breast-feeding: There is not enough reliable information about the safety of taking ginger if you are breast feeding. Stay on the safe side and avoid use.

Bleeding disorders: Taking ginger might increase your risk of bleeding.

Diabetes: Ginger might increase your insulin levels and/or lower your blood sugar. As a result, your diabetes medications might need to be adjusted by your healthcare provider.

Heart conditions: High doses of ginger might worsen some heart conditions.


Interactions with medications

Cyclosporine (Neoral, Sandimmune)

Interaction Rating = Minor Be watchful with this combination.

Talk to your health provider.

Taking ginger two hours before taking cyclosporine (Neoral, Sandimmune) might increase how much cyclosporine (Neoral, Sandimmune) the body absorbs. This might increase the side effects of cyclosporine (Neoral, Sandimmune). However, ginger does not seem to affect how much cyclosporine (Neoral, Sandimmune) the body absorbs when taken at the same time.

Losartan (Cozaar)

Interaction Rating = Moderate Be cautious with this combination.

Talk to your health provider.

Taking ginger with losartan might increase the concentration of losartan in the blood and increase its effects.

Medications for diabetes (Antidiabetes drugs)

Interaction Rating = Minor Be watchful with this combination.

Talk to your health provider.

Ginger might increase your insulin levels and/or decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking ginger along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, metformin (Glucophage), pioglitazone (Actos), rosiglitazone (Avandia), and others.

Medications for high blood pressure (Calcium channel blockers)

Interaction Rating = Minor Be watchful with this combination.

Talk to your health provider.

Ginger might reduce blood pressure in a way that is similar to some medications for blood pressure and heart disease. Taking ginger along with these medications might cause your blood pressure to drop too low or cause an irregular heartbeat.

Some medications for high blood pressure and heart disease include nifedipine (Adalat, Procardia), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem), isradipine (DynaCirc), felodipine (Plendil), amlodipine (Norvasc), and others.

Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)

Interaction Rating = Moderate Be cautious with this combination.

Talk to your health provider.

Ginger might slow blood clotting. Taking ginger along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.

Metronidazole (Flagyl)

Interaction Rating = Minor Be watchful with this combination.

Talk to your health provider.

Ginger can increase how much metronidazole (Flagyl) the body absorbs. Taking ginger along with metronidazole (Flagyl) might increase the side effects of metronidazole.

Nifedipine (Procardia)

Interaction Rating = Moderate Be cautious with this combination.

Talk to your health provider.

Taking ginger along with nifedipine might slow blood clotting and increase the chances of bruising and bleeding.

Phenprocoumon (Marcoumar, others)

Interaction Rating = Moderate Be cautious with this combination.

Talk to your health provider.

Phenprocoumon is used in Europe to slow blood clotting. Ginger can also slow blood clotting. Taking ginger along with phenprocoumon might increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your phenprocoumon might need to be changed.

Warfarin (Coumadin)

Interaction Rating = Moderate Be cautious with this combination.

Talk to your health provider.

Warfarin (Coumadin) is used to slow blood clotting. Ginger can also slow blood clotting. Taking ginger along with warfarin (Coumadin) might increase the chances of bruising and bleeding. Be sure to have your blood checked regularly. The dose of your warfarin (Coumadin) might need to be changed.


Interactions with Herbs, Supplements, and Foods

Herbs and supplements that might lower blood sugar

Ginger might increase your insulin levels and/or lower blood sugar. Using ginger along with other herbs and supplements that might lower blood sugar might lower blood sugar too much. Herbs that might lower blood sugar include devil's claw, fenugreek, guar gum, Panax ginseng, Siberian ginseng, and others.

Herbs and supplements that might slow blood clotting

Using ginger along with herbs that might slow blood clotting could increase the risk of bleeding in some people. These herbs include angelica, clove, danshen, garlic, ginkgo, Panax ginseng, red clover, turmeric, and others.

There are no known interactions with foods.

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